Nei heparin ne aspirin zvingabatsira
Apo ropa rako rinovhara, mazhinji emaprotini mumuviri wako, pakati pavo Factor V, vanoshanda pamwe chete kuti zviitike izvozvo; Chinhu V Leiden inoshandiswa pakusiyana kwezvinhu zve Factor V iyo inokanganisa kuvhara ropa uye inoita kuti munhu awedzere kugadzira ropa.
Dzidza zvakawanda pamusoro peizvi mazamu akasiyana-siyana uye zvinogona kuita sei pakubata kwako nekuongorora uku.
Kopi dze Factor V Leiden Gene
Munhu anogona kuva nekopi imwe ye Factor V Leiden geni uye imwe kopi chaiyo (inoreva kuti munhu anonzi heterozygous), kana munhu anogona kuva nemakopi maviri e Factor V Leiden gene (munhu wacho ane homozygous).
Vamwe vanachiremba vanokurudzira heparin kuvakadzi vane kuora mwoyo kwakapfuura vanoedza chinyorwa che Factor V Leiden. Kumbira chiremba wako kana akakurudzira heparin, mumwe mushonga kana pasina mushonga zvachose kwauri.
Protein C Resistance
Iko Factor V Leiden gene inobatanidzawo nemamiriro ezvinhu anonzi yakagadzirwa protein C kushorwa. Puroteni C imwewo protein inobatanidzwa mukugadzirisa. Ruzhinji rwevanhu vane hutachiona hweprotini C rinoshandiswawo vane Factor V Leiden mazamu akasiyana-siyana. Saka, vakadzi vakawanda vasina kuongororwa zvakananga ku Factor V Leiden geni vanogona kuziva kuti ivo vanotakura mushure mekuedzwa vachiona nezveprotini C.
Statistics
Inenge 4 kubva muzana kusvika ku7 muzana yevanhu ndeye heterozygous ye Factor V Leiden.
Kunenge 0.06 kubva kune 0,255 muzana yehuwandu hwevanhu ndeyekutenderera ku Factor V Leiden. Kusiyana kwemadzinza ane marudzi akasiyana eE Factor V Leiden mutation; inowanzoonekwa nevanhu vanobva kuchamhembe kweEurope. Taura nachiremba wako pamusoro pekuti iwe kana iwe uri mungozi here?
Ngozi
Chiitiko V Leiden chinoreva ngozi yakawedzerwa yehutachiona hwehutachiona uye hutano hunokosha hwemagazi eropa.
Zvimwe zvidzidzo zvakawana kuti kuva neChitura V Leiden kuchinjwa kunoreva kuwedzerwa kwehutachiona hwekucheka kwemashure, zvichida nekuda kwechidiki chechivhara ropa chinodzivirira kubuda kwezvibereko kune placenta.
Kurapa
Mune pamuviri, vamwe vanachiremba vanotenda mukushandisa heparin uye / kana pasi-aspirin yepamusoro kuti vabate vakadzi vane Factor V Leiden gene uye nhoroondo yekusaparara. Pari zvino, vatsvakurudzi vachiri kudzidza chirairo ichi kuti vaone kuti inobatsira. Makiriniki akawanda ekubereka anoburudzira kuti varwere vanotora mwana aspirin panguva yekurapwa chete kana vaine matambudziko ekuvhara.
Ukama Hwakasiyana-siyana
Vatsvakurudzi vachiri kudzidza chimiro chaicho cheukama pakati pe Factor V Leiden (uye mamwe mahedheni anokonzerwa nehutachiwana ) uye kuora mwoyo kwakapfuura. Kusiyana kwehutachiona hwehutachiona hwehutachiona hwehutano hwakasiyana-siyana hwehukama nehupombwe, asi Factor V Leiden ndeimwe yehutachiona hwehutano hunofanirwa kunge huine basa mukukonzera kusaparara (kana kuti kuwedzerwa ngozi) nekuti vakadzi vane mutsika vane huwandu hwepamusoro kupererwa kwevakadzi kunze kwevakadzi vasina.
Kutsvakurudza kuripo kunoratidza kuti Factor V Leiden inogona kuita nharo mukusavhiringidzika kunoitika mushure memavhiki gumi asi hazvikwanisi kuve chinhu chinokonzera kupererwa kwepakutanga.
Vanachiremba vakawanda vanoedza ku Factor V Leiden sechikamu chekudzoka kwepabonde kwekuongorora uye kukurudzira kurapwa kune avo vanoedza vanoona zvakanaka.
Sources:
Coulam, CB, RS Jeyendran, LA Fishel, naR. R. Roussev, "Nyama dzakawanda dzepachirwere zvinokonzerwa nemafuta panzvimbo yezvinhu zvakasiyana-siyana zvinokonzerwa nejenjeri zvikonzero zvinowanzoita kuti pave nemararamiro akasiyana-siyana." American Journal of Reproductive Immunology May 2006.
Foka, ZJ, AF Lambropoulos, H. Saravelos, GB Karas, A. Karavida, T. Agorastos, V. Zournatzi, PE Makris, J. Bontis, uye A. Kotsis, "Factor V leiden uye prothrombin G20210A kuchinja, asi kwete methylenetetrahydrofolate kunoderedza C677T, inosanganiswa nekudzokorora kwemasimba. " Feb 2000.
Jivraj, S., R. Rai, J. Underwood, naL. Regan, "Kuchinja kwechirwere chemafuro pakati pevakaroorana vanowanzopererwa." Kuberekwa kwevanhu muna May 2006.
Reznikoff-Etievan, MF, V. Cayol, B. Carbonne, A. Robert, F. Coulet, naJ. J. Milliez, "Factor V Leiden uye G20210A kuchinja kwemaitiro kunokonzera kukanganisa kwekupererwa kwemazuva mashoma. ' BJOG Dec 2001.
University of Illinois - Urbana / Champaign, "Patient Resources: Factor V Leiden." Hematology Nhare Reji .
Walker, MC, SE Ferguson, naVM Allen, "Heparin kuvakadzi vane pamuviri vane zvirwere zvinowanikwa kana kuti vanowana nhaka." The Cochrane Library 21 Jan 2003.