Genetic uye Environmental Factors Zvingaita Neural Tube Kutadza
Anencephaly rudzi rwekuremara kwekuberekwa umo zvikamu zvakakosha zveuropi hwecheche nehenya rinokundikana kuumba. Zvinosuruvarisa, vana vacheche vanobatwa newaye anowanzofa kana vafa kana vazvarwa. Kunyange kana akaberekwa ari mupenyu, vacheche vane anencefaly vanofa nguva dzose mumazuva mashomanana ekuberekwa. Hakuna kurapwa kunogona kuchinja kufungidzira.
Kunzwisisa Neural Tube Defects
Anencephaly chirwere chetachiona chinokonzerwa neural (NTD), iyo inoberekwa kukanganisa kunosanganisira uropi, musana kana musana weropa.
Iyi ndiyo mamiriro ayo iyo inovandudza neural tube haifaniri kupfiga zvakanaka panguva yekukura kwechecheche-kare munguva yekutanga katatu. Neural tube zvikanganiso zvine zvakasiyana-siyana zvakanyanya, kubva pane zvido zvishoma zveutano kusvika kuva 100 muzana vanofa.
Pamusoro pemhando yakakura yeyo tsvina ndeyekunyanyisa, chimwe chezvinhu zvinoparadza zvakanyanya vabereki vanotarisira vanogona kugamuchira panguva yekuzvitakura. Zvinosuruvarisa, vana vacheche vane anencefu havagoni kuwana ruzivo kana kuita mabasa ehupenyu hwehupenyu nokuti vanoshaya zvikamu zvinokosha zvehuropi hwavo. Nemhaka yokuti dhehenya rinobatwawo nehutachiona, vana vacheche vane anensefa kazhinji vanowanzoora muviri uye zvikamu zvehupi hwavo zvinogona kubudiswa pachena.
Maitiro Azvo Anoongororwa
Anencephaly kazhinji inowoneka paine ultrasound neyechipiri katatu.
Nzira yekutanga pamusoro pekuongororwa ingangodaro isina kukanganisa muAfrefetoprotein (AFP) kuongororwa ropa .
Iko kuongorora kweAAPP kunogona kuona 80 kusvika ku90 muzana yevana vanove neural tube defect.
Amniocentesis inogona kushandiswa mukurapa pamwe chete. Anensephaly diagnosis haifaniri kunge yakanyengera.
Zvinokonzera
Anencefaly inoratidzika inokonzerwa nekubatanidzwa kwemajini uye yezvakatipoteredza. Kubatanidza kwezvinhu izvi kunokanganisa kugadzika kwee-neural tube, iyo inowanikwa pakati pevhiki yechitatu nechina yekubata.
Izvo zvakananga zvezvinhu zvinoshanda mune anencephaly uye dzimwe neural tube zvikanganiso zvisati zvanyatsonzwisiswa. Kunyangwe tisingazivi zvikonzero zvinokonzerwa neanencephaly, zvimwe zvinokonzera ngozi zvinowanikwa, kusanganisira kudya kwakakwana kwe folic acid.
Folic Acid uye Neural Tube Defects
Pane humwe uchapupu hwokuti kuva nehutano hwakakwana hwe folic acid musati mimba kunoderedza dambudziko rekuva nemwana unobatwa nechipi nechipi chinonzi neural tube defect, kunyange zvazvo zvikonzero izvi zvisingazwisisiki. Ichi ndicho chikonzero vanachiremba vanokurudzira vakadzi vose vezera rekurera kutora folic acid kuwedzera uye kudya kudya kwehupfumi nguva dzose. Usamirira kusvikira watova nepamuviri. Vakawanda vanovhiya vanoita kuti vatange kutora folic acid kuwedzera kwemwedzi mitatu vasati vaita pamuviri.
Izvozvo zvakati, kusuruvara kunogona kuitika kunyange kana amai vachidya kudya kwakakwana, saka hazvikwanisi kudzivirirwa uye zvechokwadi haisi mhosva yeipi kana ichiitika. Zvechokwadi, chidzidzo chegore ra2015 chichiongorora kuwanda kweealural tube kusimba kwakadai seanencephaly muEurope, yakaona kuti hakuna kumbove nekuderedza kudarika kwezviitiko zvekukanganisa uku, pasinei nekurudzirwa kwakapararira kuwedzera folic acid yakave iri munzvimbo makumi emakumi emakore.
Kune rumwe rutivi, zvose zvinoitika uye kuoma kwepasiporesi yeumusana wehutachiona (spina bifida) yakaratidzika kuderera munzvimbo dzenyika umo zvokudya zvinogara zvichiwedzera ne folic acid.
Genetic Mutations
Isu tangotanga kudzidza nezvemagadzirirwo emagetsi anokwanisa kuwedzera dambudziko rekunyengera. Kutaura nemupa mazano anokwanisa kukubatsira kuziva kana nhaka ingave yakaita basa. Asi izvo zvakati, nhaka inogona kungoreva kuti kune chikonzero chekushongedza neural tube, asi kwete kuti kuchinja uku kunoita kuti neural tube zvikanganiso.
Zvimwe Ngozi Dambudziko
Zvimwe zviitiko zvinogona kuita basa mukuvandudza kwekunyanyisa kunosanganisira hukama hwehukama, hutsika hwehutano, makore ekuberekwa, uye zvakatipoteredza kune kuwedzera kune folic acid.
Ikozvino pane kuongororwa kwakaenderera mberi muHashington nyika kuongorora boka revana vacheche vane anencephaly uye vachitarisa zvinokonzera zvinokonzera, kana izvi zvingave zviri mazamu (zvakabatana nezvimwe zviri mu folic acid mugwagwa), kutaridzirwa kune zvakasikwa zvepanyika uye zvehupfumi, nezvimwewo.
Dambudziko rekudzokazve
Vabereki vane mwana ane anencefa inogona kuva nechina kusvika kune gumi mukana wekuwana mwana akabatwa neal neural tube kukanganisa mumubhedha munguva yemberi, kunyange zvazvo neural chaiyo yepasipo chiremera chingave chisina kuchena. Vanachiremba vanogona kupa mazano ekutora mazinga akawanda e folic acid vasati vava nemimba zvakare uye vangakurudzira kuti vaviri vacho vanoshanda neine genetic advisor zvakare.
Zvaunofanira Kuita Mushure mekunyatsoziva
Chisarudzo chezvinozoita mushure mekunge uchitarisa unensephaly kunogona kushungurudza mwoyo.
Vabereki vakawanda vanosarudza kugumisa kuberekwa mushure mokunge vawana chirwere chekurwadziwa, vachiziva kuti pane zero mukana kuti mwana achararama. Kupedza kubata kunogona kubatsira vabereki kuti vafambe mberi uye vatange kushungurudza. Neural tubes ndeimwe yezvikonzero izvo pamuviri unogona kubviswa nokuda kwezvikonzero zvekurapa .
Vamwe vabereki vangave vane zvakasimba zvechitendero kana zvimwe zvavanoda kubvisa pamuviri, uye vangasarudza kutakura pamuviri kutora nguva uye ruzivo rwakakwana kuti mwana haangararami kwemazuva mashomanana.
Kana uri kutarisana nesarudzo iyi yakaipa, iva nechokwadi chekutora nguva yako uchiita chisarudzo uye kuita izvo zvinonzwa zvakakunakira iwe nemumwe wako. Zvipe iwe nzvimbo yekushungurudza kurasikirwa kwemwana .
Kukunda Kana Mwana Achizivikanwa
Zvakanaka kuva nehasha, kusuruvara, kana kuve nemamwe manzwiro. Chipatara chako chingave nevanopa mazano ekurwadziwa, uye pane mapoka akawanda ekutsigira anowanika paIndaneti inotarisa vakaroorana vanotarisana neanencephaly diagnosis. Mapoka ekutsigira anencefaly anowanzotarisirwa kune imwe nzira yekuita nayo pakubata nepamuviri-kana izvo zvinoreva kubvisa pamuviri kana kutakura kusvika nguva-naizvozvo iwe unogona kutarisa-tarisa kuti uwane iyo inonyatsokodzera zvaunoda.
Kune Mhuri Neshamwari dzeMubereki
Kana iwe uri nhengo yemumhuri kana shamwari yeumwe munhu anotarisana nehutano neanencephaly, mudiwa wako achada rubatsiro rungagona kupa. Chero mararamiro ekurasikirwa, zvisinei kuti izvo zvinoreva kusununguka pamuviri, kuberekwa, kana kufa kwechecheche kwakaoma, asi anencephaly inowedzera imwe nzvimbo. Kunzwa pamusoro pe folic acid uye zvakadai zvinogona kutungamirira vabereki kuzvipa mhosva, uye nzira dzinogona kuitika ndeyekutambudzika, sezvinoedza kuita sarudzo pakati pekutora kodzero kuva mhepo yakachena shark inoputika, kana kuruboshwe runoita nyoka yakazadza rwizi.
Sezvinovabatsira zvikuru, edza HERE kusaunza zvinokonzera zvinokonzera anencefa newaunoda. Iyi mibvunzo inokosha, asi inofanira kusiiwa nevaya vari kutsvakurudza zvikonzero, kwete amai vanochema. Iwe unogona kuva nechokwadi chokuti vadiwa vako vakatotambudza ivo zvakakwana nezvinoita zvinokonzera. Pamwechete, ndapota musaunza nyaya dzakadai sedambudziko rekuti neural tube chiremera chinogona kuitika zvakare. Vadiwa venyu vari kushungurudzika, uye vanoda nguva ino kuti vatsungirire kushungurudzika kwavo kwemazuva ano nhasi.
Pakupedzisira, kunyange dai iwe ukazoita sarudzo yakasiyana kana iyi iri iwe pachako uchinge uine pamuviri, somuenzaniso, kana iwe ukasarudza kuenda kune imwe nguva uye mudiwa wako ari kusarudza kugumisa, kana kana iwe ukazoguma asi iwe waunoda ari kusarudza kuenda kusvika kumutambo, yeuka kuti uyu hausi iwe sarudzo yako yekuita. Uye, netariro, hauzombodi kuzviitira iwe sarudzo, nokuti, sezvatinoziva, vanhu vanowanzotaura kuti vangasarudza kurapwa kumwe kana vachitarisa mamiriro kubva kure, asi vasarudza nzira yakasiyana kana vakasangana nechisarudzo chimwechete ivo pachavo muhupenyu chaihwo. Vadiwa venyu vanoda kusarudza zvakakosha kwavari, kwete mumwe munhu. Pasinei nechisarudzo chavo vanoda rubatsiro rwakakwana nekutarisira.
Sources:
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Singh, N., Kumble Bhat, V., Tiwari, A. et al. Mutemo weHomozygous mu TRIM36 Zvinokonzera Autosomal Kuyeuka Anencephaly muIndia Family. Human Molecular Genetics . 2017 Jan 13. (Epub mberi kwekudhinda).