Idzidziso Inofanirwa Kubatsira Kushandiswa Kushandura uye Zvingave Zvakakunakira Iwe
Hatching yakabatsirwa inobatsira teknolojia yekuberekwa iyo dzimwe nguva inoshandiswa pamwe chete neyakakurumbira IVF chirwere . Hatching inotsigirwa inofungidzirwa kuti inogona kubatsira ne embryo implantation uye inowanzokurudzirwa kana pave zvichidzokororwa kusina kutsanangurwa kweVF kana kuti kune varwere vane chirwere chisina kunaka.
Kunyange zvazvo mamwe makiriniki anoshandisa kubatsirwa kubvisa nguva dzose, American Society of Reproductive Medicine (ASRM) haina kukurudzira izvi. Izvi ndezvokuti kubatsirwa kubatsirana hakuratidzirwe kuvandudza mararamiro ekuzvarwa patsva. Kunyanya, sekune hupi hwehutano hwekuberekera, pane zvimwe zvinodhura uye njodzi yekushandisa kushandiswa kwekudzivirira.
Pane chiremba wako akakurudzira kukubatsira kubvumira iwe here? Hezvino izvo zvaunoda kuziva.
Mawere Anobhururuka Sei?
Kuti unzwisise kubatsirwa kubatsirwa, kutanga, kunobatsira kunzwisisa hutachiona hwemazuva emumwana.
Iwe usati watora mucheche, unotanga ne oocyte , kana mazai. Ioocyte ine proteine-shell yakaipoteredza inozivikanwa seyi zona pellucida. Iko zona pellucida ine mabasa akawanda ekugadzirwa kwebumbiro, uye izvi zvinoshanduka sechimbryo ichikura.
Zuva risati rava mucheche, iyo zona pellucida fuses nemasero emasero. Ichi ndicho kutanga kwehutano hwekuita. Kamwe kana imwe sermin cell inopinda muhombe uye inosvina mazai, iyo pellucida inowedzera. Izvi zvinodzivirira huwandu hwemajeri mashoma kupinda muzvino-yakagadzirwa zygote.
Iyo yakaoma yakavharawo inobatsirawo kudzivirira iyo embryo kubva pakuisa nguva isati yasvika mu fallopian tubes (iyo inogona kukonzera ectopic pamuviri ). Iyo inochengetedzawo mazhinji masero e blastocyst pamwe chete.
Sezvo zygote inofamba ichienda pasi kune hutachiona uye inowedzera mu blastocysts, iyo pellucida inowedzera uye inotanga kuonda uye kuipa. Panenge zuva rechina rekufambira mberi, iyo zona pellucida inoputika uye blastocyst / embryo inobuda, ichisiya pasi pete-protein shell. Uyu ndiwo mushonga wokudzivisa embryo.
Mumazuva mashomanana ekubhururuka, blastocyst inozviisa mukati me endometrium . Pasina hatching, blastocyst haigoni kuzviisa mukati mehuta reuterine. Izvi zvinoreva kuti pamuviri ungakundikana kuitika.
Chii Chinobvumirwa Kubhadhara?
Munguva yekurapwa kweVIVF , kubereka kunoitika mubazi. Asi sevamwe vaviri vakaroorana vakapfuura nehutano hweVIV, vanoziva kuti, kuva nehutachiona husina kubereka hazvirevi kuti vanove nepamuviri. Imbryo inotamirwa inofanira kuzviisa mukati me endometrium uye "tsvimbo" yokuti pamuviri uite.
Kusvikira 85 kubva muzana yemambrus akaendeswa haafaniri "kunamatira." Pane maonero ekuti nei ichi ichiitika, uye chimwe chezvinhu izvi ndeyekuti embryo haibvaki zvakanaka. Izvi zvinogona kuitika nokuti embryo inowanzove yakaoma yakaoma, kana kuti chimwe chinhu chiri mubasa rebazi (tsika dzinoshandiswa kuchengetedza embryo chipenyu, cryopreservation chemikemikari, nezvimwewo) zvakanyangadza kuparadzanisa kushandiswa kwekudzivirira.
Hatching yakatsigirwa inoshandiswa kuvhara chero zvipingamupinyi zvipi zvinodzivirira kuputika nekuvandudza matanho ekusimbiswa (nekuzvitakura) kubudirira.
Nzira Dzakatsigirwa Hatching: Zvakaita Sei
Iwe unogona kufunga kuti kubatsira kubvisa nguva dzose kunosanganisira kuita zvishoma "kuputsa" kana kubvarura mu zona pellucida. Asi izvi hazvisi izvozvi. Kune nzira shomanana dzinowanikwa, uye mairi ese embryo anobata izvi zvakasiyana. Kune humwe hutano uye hunovhiringidza kune imwe neimwe nzira, uye unyanzvi hwomudzidzisi nyaya:
- Mechanical hatching : Nechirongwa ichi, embryologist inochengetedza embryo kugadzikana nekubatsirwa kwepipette, paunenge uchishandisa micro-sindano kupisa kuburikidza ne zona pellucida, enda pasi pechiganda kwechinguva, uye wozobuda kune imwe mugumo. (Fungidzira uchidhonza mutsara wakaonda kwazvo pedyo nemumbryo.) Zvadaro, nzvimbo iri pakati pemapctures maviri inonatswa kusvika zvishoma. Zvakaoma kudzora uswa hwekuvhura nemugwagwa.
- Kuwedzera kweMechanical yekanda : Neyi nzira, iyo pellucida haina kuputswa. Pane kudaro, hydrostatic rinomanikidzwa inotangwa pasi peiyo shell, kuti iite kuti iwedzere. Mhedziso yemugwagwa uyu unouya kubva pakuwedzera kwechimiro chegomba rekunze panguva yekuchenesa.
- Kachirasi hatching : Iyi nzira inosanganisira kushandisa kemikari inozivikanwa seTyrode's acid. Zviduku zviduku zveasiti zvinoshandiswa kune zona pellucida kusvikira shell yakaputsika. Zvadaro, embryo inokurumidzirwa kucheneswa kuitira kuti irege kusakosha asidi.
- Kubvongodza : Nokugadzira, kushandiswa kwemhepo kunoshandiswa kugadzira kuvhura kwekodhi. Iyi nzira inoshandisa chimwe chinhu chinonzi Piezo teknolojia.
- Laser-yakabatsirwa kubvisa : Kushandisa laser yakakosha kuputsa iyo zona pellucida imwe imwe nguva inogona. Laser-inobatsira kubvisa hunoita kuti humwe humwe hutungamiri hwehupamhi hugadziridzwe, huri nani kupfuura kushandiswa kwemashini nemushonga (sezvinotsanangurwa pamusoro).
Pamashoko ose, laser-assisted hatching inogona kunge iri yakachengeteka uye inobudirira zvikuru. Zvisinei, haisi mairi embryology labori yakagadzirirwa kuita iyi teknolojia. Kushandiswa kwemakemikari kunowanzoshandiswa. Nezvese nzira idzi, unyanzvi uye ruzivo rwehutano hwembryologist zvinogona kuita kusiyana kukuru.
Ngozi dzeHachipiri Hatching
Chero kushandiswa kana kupindira nehucheche kuchave kunosanganisira ngozi. Imwe inogona kuisa njodzi yekubatsira kubvisa ndeyekuti embryo ichakuvara zvakashata. Izvi zvinogona kuitika mushure mekuberekwa kwemukomana kana shure. Chero zvazvingaitika, kutakura hakungagumisi.
Zvimwe zvisinganzwisisiki, rimwe dambudziko rekubatsira kubvisa hutachiona hwehutachiona huchakandwa kunze uye embryo ichakundikana kubvisa zvizere kubva ku zona pellucida.
Imwe njodzi yekubatsira kubvisa hutinning is, in particular monozygotic twinning. Monozygotic mapatya zvakafanana namababa, anouya kubva kune rimwe dza uye mushure mumwe. Kuderedza kwave kuchiwedzerwa panguva yakarongeka yeVIV, uye tsvakurudzo yakawana kuti yakabatsira kubvisa kuwedzera kwangu kuwedzera kwengozi. Kunyange zvazvo vose vane pamuviri vakawanda vane mungozi, monozygotic twin pregnancy inouya nematambudziko makuru kune amai nevana. Kunyange zvakadaro, mukana wekutinhira uri pasi, unoitika zvishoma pane 1 muzana yenguva.
Iwe unogona kunge uchishamisika kana kubatsirwa kubhadhara kunowedzera dambudziko rekuremara kwekuberekwa. Chidzidzo chikuru chekudzoka kwemazana anenge makumi matatu nezviuru makumi matatu nezviviri chakaona kuti njodzi yekuberekwa kusakanganiswa haina kuwedzera zvakanyanya nemazai ayo akashandiswa nekubvamburwa kubatsiriwa, zvichienzaniswa nemiganhu ye IVF iyo yakabatsiridzirwa kubvisa haina kuitika.
Inobatsira Kubhadhara Kuvandudza Mitengo Yakabudirira yeVIVF?
Mubvunzo mukuru ndewokuti, hongu, unofanirwa here? Inobatsira kubhadhara kunobatsira here kuenda kumba kumba? Mhinduro yacho yakaoma zvakaoma.
Kubvunzurudzwa kweCochrane pamubatsiro wekudzivirira-iyo yakaongororwa zvidzidzo makumi matatu nemakumi matatu nemashanu, vakadzi vane chikwata che1992 nemadzimai 5 728-vakawana kuti vakabatsira kubvisa zvishoma zvishoma kuwedzera kamuviri yekuita pamuviri. Zvisinei, mararamiro ekuberekwa anorarama haana kuwedzera.
Kurarirwa nekuberekwa kwehuwandu kune zvakakosha kuongorora pane chirwere chepamuviri pamuviri kubva pane chinangwa mune chero kurapwa kwekubereka kunotora kumba kumwana-kwete kungova nemimba yekuzvidzivirira kwakanaka.
Zvinosuruvarisa, ruzhinji rwekutsvakurudza kwekubatsira kubhadhara kunongoratidzira kliniki yekubata pamuviri, uye kwete mararamiro ekuzvarwa patsva. Avo avo vakatarisa kumararamiro ekuberekwa aripo havana kuwana mukana. Tsvakurudzo yakawanda inofanira kuitwa.
Chimwe chidzidzo chakawana kuti kana rubatsiro rwekudzivirira rukaitwa pa "hutano hwakanaka" embryo, kutora mimba kwakaderera. Migumisiro yakasiyana-siyana zvichienderana nezera rezera panguva yaibatsirwa kubvamburwa kwakaitwa pazvakanaka kune mashoma embryos. Izvi zvingareva kuti kubatsiridzirwa kubvisa kwete chete hakuzobatsiri avo vane maitiro akanaka, asi zvinogona kukuvadza mikana yavo yekubudirira.
Ndivanaani Vanogona Kubatsirwa Nokubvambiswa Kunobatsira?
Pane humwe humwe humwe huripo huchibatsira hutachiona hunovandudza hutachiwana hutachiwana huwandu nevarwere vano:
- Wakave nemakore maviri kana kupfuura akakundikana IVF maitiro
- Iva nehutu hwakanaka hwembryo
- Vakuru kune makore makumi matatu nemasere
Zvaifungidzirwa kuti kubatsira kuvhara kungave kwakakosha kuedza nechando chisina kuvhara kuenderera mberi, asi izvi zvingave zvisina kudaro. Muzvokwadi, kumwe kuongorora kwakawana kuti kubatsirwa kubvongodzwa mukati mechando mazai embryo kunogona kuderedza kuderera kwemaitiro ekuzvarwa patsva.
Mutengo Wekubatsirirwa Hatching
Pasinei nekurumbidzwa kweAJR, ndiani anorayira kurwisa kushandiswa kwekushandiswa kwebatsiri, mamwe makiriniki achiri kuipa kune varwere vose. Mune makiriniki, mari yekubatsiridzirwa inogona kunge yave "yakabatanidzwa" mumutengo weVF .
Kune makiriniki anowedzera-onobatsira kubhadhara, mari inogona kubva kubva ku $ 200 kusvika ku $ 700, paavhareji. Kunewo makiriniki mashoma anopa teknolojia ye "vakasununguka," kana vachifunga kuti inogona kubatsira.
Shoko Rinobva Kunyanya
Paunenge uchitaura nezvekurapa kweVF, zvinogona kuedza kugamuchira kana kuda kushandisa zvose zvigadzirwa zve "technology-added" zvinopiwa. Zvinogona kuonekwa semamwe rubatsiro zvinofanira kugara zvichiita kuti muve nemukana wakanaka wekubudirira. Asi zvimwe hazvirevi kuti nguva dzose zviri nani.
Nokuti hapana humwe humwe huchapupu hwakakwana hwokuratidza kubatsirwa hatching hunovandudza mararamiro ekuberekwa ari kurarama, ASRM inorayira pamusoro pekushandisa nguva dzose kwekombiyuta. Kana kliniki yenyu inoshandisa kushandiswa kubatsirana nevarwere vose, taurai nachiremba wenyu nezvekuti nei vachifunga kuti izvi zvakakunakira iwe. Iwe unogona kuchinja teknolojia iri pasi.
Zvisinei, kune mamwe mapoka emarwere, anobatsira kubvambura kunogona kubatsira. Sezvo nguva dzose, taura nachiremba wako pamusoro pemamiriro ako ega.
> Sources:
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