Zvinosuruvarisa, ichi chinouraya chromosomal disorder hachina chirwere
Matambudziko eGenetic uye chromosomal anogona kuita zvakasiyana-siyana uye zvinogona kuita kuti utano hwomwana huve hwakawanda . Migumisiro inogona kuva chero chinhu kubva pane zvinetso zvoutano zvishoma kusvika "kusawirirana nehupenyu," zvinoreva kuurayisa kunouraya.
Triploidy chirwere chinowira pamagumo ekupedzisira kwetambo. Ruzhinji rwemucheche runoita triploidy kufa asati aberekwa uye avo vanoita kuti ive izwi rinowanzopona mumwedzi mitanhatu yeupenyu.
Chii chinonzi Triploidy?
Vanhu vane imwe neimwe inofanirwa kuva nemakromosomes 46 (maviri maviri). Munhu anowana hafu yemakromosomes maviri kubva kumubereki mumwe nomumwe. Triploidy zvinoreva kuti mwana ane mapepa matatu echromosome imwe neimwe muchitokisi, kwete maviri, achiita ma-chromosomes 69. Triploidy inogona kutora kubva kune rimwe chete iri rinogadzirwa nemaviri maviri kana kubva pane zvakakanganisika mumasero ekuparadzanisa zvinokonzera kuti mazai kana chirume chive nemakromosomes makumi mana makumi mana nematanhatu panguva yekudyarwa.
Aina
Kazhinji zviitiko zve triploidy zvinosanganisira "zvakazara" triploidy, zvinoreva kuti masero ose omumuviri akabatanidzwa. Muzviitiko zvisingawanzoitiki, triloidy inogona kuva "mosaic," zvinoreva kuti mamwe masero emumuviri ane makopi matatu echromosome imwe uye vamwe vane mararamiro ezvigadzirwa makumi mana emakromosomes. Kune humwe uchapupu hwokuti vanhu vane maratiro epafiriki vangasanyanya kuderedzwa nehutano kupfuura avo vane triploidy yakazara. Asi kunyange nekwenyendo patroidy, chirevo hachina kunaka.
Ukama Kumusarura Molar Kuberekwa
Mimwe mimba inobatwa ne triploidy ichabatwawo nechikamu che hydatidiform (partially molar pregnancy ), zvinoreva kuti pane chikamu chisina kujairika chingaita, muzviitiko zvisingawanzo, chinokonzera kukanganisa upenyu kune amai. Zvisinei, haisi mhando dzose dze triploidy dzichava nhumbu yekurera.
Pane kumwe kunetseka kuti triploidy inokonzerwa nehuviri yemumumanyo inosanganisa mazai ega inogona kunge yakakonzera kukanganisa kunokonzera kwemashure kupfuura triploidy inosanganisira egg kana kuti mbeu ine ma chromosomes 46 kubva pakutanga. Asi izvi hazvina kuratidzwa.
Kuziva
Triploidy inogona kuongororwa kuburikidza nekuongororwa kwemajini chete-kureva amniocentesis , kuongororwa ropa kwechechecheche, kana karyotyping yezvisikwa kubva mukurasikirwa pamuviri. Kuongorora miedzo yakadai sey ultrasound uye alphafetoprotein kuedza kunogona kuratidza zviratidzo zvekuyeuchidza zve triploidy. Asi izvi zvidzidzo hazvigone kusimbisa kufungidzirwa kwe triploidy. Zvikwereti zvepamusoro hCG mazinga zvinogona kuwanikwa mune zvimwe zvekudzivirira ne triploidy, uye an ultrasound inogona kuratidza unhu hutsika hunobatanidzwa nehutachiona hwemhara.
Prognosis
Zvinosuruvarisa, triploidy nguva dzose inouraya uye hapana mushonga kana kurapwa kwechiitiko. Sezvambotaurwa pamusoro apa, inenge yose (inopfuura 99%) yevana vane triploidy vasati vashandurwa kana kuti vasati vaberekwa. Kune avo vanoberekwa vari vapenyu, vazhinji vanofa mumaawa kana mazuva mushure mekuberekwa. Vana vashoma vane vana vane triploidy vave vakararama mwedzi mishanu kana kupfuura. Asi mitsara iyi haifaniri, uye kazhinji, vacheche vanopona kwenguva yakareba vane mafirimu matatu, panzvimbo pokufamba kwenguva yakazara.
Vana vane njodzi vanowanzova nezviremera zvakasiyana-siyana zvekuberekwa uye kukanganisa kukura kwakanyanya.
Dambudziko rekudzokazve
Vanotsvakurudza havana kuwana chero zviratidzo zvinokonzerwa nehutachiwana hwekutora pamuviri kunoshungurudzwa ne triploidy. Kunyangwe nemakore ekuberekwa hakuratiki sechinhu chinokonzera. Nhamba shomanana yevakadzi inogona kunge yakave nokupererwa kwepamusoro kwakabatwa ne triploidy. Asi mune dzakawanda mamiriro ezvinhu, triploidy inowanzoerekana yaitika uye inongova imwe nguva yengozi isingadzokeri munguva yekusununguka. Kana iwe wakagamuchira triploidy kuongororwa mushure mekuongororwa kwezviviri kubva pakuparara kana kuberekwa, maitiro ayo ari kuitika zvakare haana zvishoma.
Kana Mwana Wako Ane Triploidy
Mamwe mashoko akawanda anokanganisa pamusoro pe triploidy ari kunze uko, saka kana mwana wako akaonekwa kuti ane chirwere ichi panguva yekudzivirira kana sechecheche, iwe unogona kushambira nemanzwiro, kusanganisira kushaya simba, kuvhiringidzika, uye kuchema. Chinhu chokutanga chaunoda kuziva ndechokuti iwe hauna kuita chero chinhu chipi zvacho kuti chiitike ichi, uye hapana chakakwanisa kuzvidzivirira kuti zvirege kuitika. Zvakanaka kuchema (kana kunzwa chero zvimwe zvaunogona kunzwa).
Kana mwana wako akaonekwa kuti ane triploidy kuburikidza neamniocentesis (iyo inowanzoitwa pakati pevhiki 15 nevhiki yekubata pamuviri), iwe uchada kubvunzwa kana uchida kuramba uchiita pamuviri. Ichi ndicho chisarudzo choga uye iwe unofanira kuita izvo zvinoshanda kwauri. Vamwe vakadzi vanosarudza kupedza pamuviri vane hutachiona hunouraya , asi vamwe vanosarudza kuramba vachiita pamuviri, kunyange zvazvo vachiziva zvinotarisirwa kuita. (Cherechedza kuti kana uchinge uine hutachiwana hutachiona hwemhepo , hapana mukana wekuti mwana azvigadzirire kusvika pakuzvarwa uye ave akaberekwa ari mupenyu.Uchiremba wako achakurudzira kuguma kuti udzivirire zvinetso zvakakomba zvingakanganisa hutano hwako.)
Kana iyo triploidy kuongororwa inouya mushure mekunge mwana wako atozvarwa, inyaya yakanaka kutaura nemupa mazano maererano nezvinofanira kutarisira, maererano nekuchengeta mwana wako. Nguva zhinji, chirongwa chinorayirwa ndechokupa nyaradzo yekuchengetedza panzvimbo pokutsvaga mazano anobatsira. Iko kune mapoka akawanda ekutsigira vabereki vecheche vane chirwere chakakomba chromosomal, uye iwe ungawana izvi kuti zvinyaradze sezvaunosangana nemashoko aya.
Sources:
Brancati F, Mingarelli R, Dallapiccola B. Kakawanda triploidy yemukadzi kubva kumwana. Eur J Hum Genet 2003; 11: 972-974.
Triploidy. Texas State Health Dept. http://www.dshs.state.tx.us/birthdefects/risk/risk24-triploidy.shtm